Quad Jumbo Nasal Spray

Description What is the Quad Jumbo Nasal Spray? This is an ultra-strength, large-volume formulation of Melanotan II (MT-II) nasal spray —containing 40mg MT-II in a 20ml bottle. MT-II is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that activates melanocortin receptors and has been extensively studied for its role in stimulating melanogenesis — the biological process by which melanin pigment is produced. The compound, receptor pharmacology, and research profile are identical to the double-strength 20mg/10ml nasal spray formulation. The Quad Jumbo format is distinguished by its volume — suited to longer-duration research protocols or multi-subject studies requiring larger quantities of MT-II via the nasal route without frequent reformulation. What Researchers Are Exploring Melanogenesis & Pigmentation MT-II stimulates MC1R on melanocytes, upregulating tyrosinase and driving melanin synthesis. Published research has documented pigmentation responses across a range of UV exposure conditions and baseline skin types. Melanocortin Receptor Pharmacology As a non-selective agonist across MC1R, MC3R, MC4R, and MC5R, MT-II has been studied for receptor binding profiles and downstream signalling effects. Research continues to explore subtype-selective outcomes and the pharmacological consequences of broad melanocortin activation across pigmentary, metabolic, and neurological pathways. Energy & Metabolic Pathways MC3R and MC4R agonism by MT-II intersects with the melanocortin system’s role in energy homeostasis, appetite regulation, and leptin pathway signalling — areas of ongoing metabolic research independent of MT-II’s pigmentation applications. Extended Nasal Delivery Protocols The 20ml volume allows for sustained nasal delivery protocols without reformulation. Comparative bioavailability research between nasal and injectable MT-II delivery remains of interest, and the larger format enables longer comparative study periods under consistent formulation conditions. Worth Noting This formulation provides 40mg MT-II across 20ml four times the standard nasal spray formulation suited to extended research periods or protocols requiring larger total peptide quantities. For research use only. Not approved by the TGA or FDA.