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MEDIK8 Intelligent Retinol 3TR fast-absorbing serum, formulated with 0.3% retinol, is perfect for those new to vitamin A, or as an upgrade from Night Ritual Vitamin A. How to use: How to use: After cleansing in the evening, massage 4 drops of retinol across the face, neck and décolletage. Follow with your regular Medik8 moisturiser or facial oil. Retinol application should be phased in gradually. Use twice a week for the first 2 weeks, every other night for the next 2 weeks, then every night. Consult a doctor if breastfeeding or pregnant.